Associate Professor

Phone: 86(27) 87792025


Academic Areas: Bioinformatics

Research Interests: Protein structure and function prediction; protein interaction network

Academic Degrees

PhD in System Science, 2006, Huazhong University of Science and Technology,China

BS in Material Science and Engineering, 1997, Huazhong University of Science and Technology,China

Professional Experience

Associate Professor(Nov,2010–), School of Life Science and Technology , Huazhong University of Science and Technology, China

Visiting Scholar(Sep,2011-Sep,2012), Department of Computational Medicine and Bioinformatics, University of Michigan(Ann Arbor), USA

Post-Doctoral  Fellows(Nov,2006-May,2009), School of Life Science and Technology, Huazhong University of Science and Technology, China

Lecturer (Mar,2008–Nov, 2010), School of Life Science and Technology , Huazhong University of Science and Technology, China

Selected Publications

1. Yan Wang, Jouko Virtanen, Zhidong Xue, John J. G. Tesmer, Yang Zhang. Using iterative fragment assembly and progressive sequence truncation to facilitate phasing and crystal structure determination of distantly related proteins. Acta Crystallographica Section D, 2016 72(Pt 5):616-628

2. Yan Wang, Mingxia Wang, Sanwen Yin, Richard Jang, JianWang, Zhidong Xue and Tao Xu. NeuroPep: a comprehensive resource of neuropeptides Database-The Journal of Biological Databases and Curation, 2015:bav038

3. Zhidong Xue, Richard Jang, Brandon Govindarajoo, Yichu Huang, Yan Wang. Extending Protein Domain Boundary Predictors to Detect Discontinuous Domains. PLOS ONE, 2015.10(10):e0141541

4. Jianyi Yang, Yan Wang, Yang Zhang ResQ: An approach to unified estimation of B-factor and residue-specific error in protein structure prediction. Journal of Molecular Biology, 2016 428(4): 69-701

5. Richard Jang, Yan Wang, Zhidong Xue, Yang Zhang. NMR data-driven structure determination using NMR-I-TASSER in the CASD-NMR experiment. Journal of Biomolecular NMR, 2015, 62: 511-525

6. Zhidong Xue, Dong Xu, Yan Wang, Y Zhang. ThreaDom: Extracting Protein Domain Boundary Information from Multiple Threading Alignments. Bioinformatics, 2013,29: i247-i256

7. Yan Wang, Zhidong Xue,Gang Shen, Jin Xu. PRINTR: A new method forpredicting protein-RNA interacting Sites. Amino acids. 2008,35:295-302

8. Yan Wang, Zhidong Xue, Jin Xu. Better Prediction of the Location of α-turnsin Proteins with Support Vector Machine. PROTEINS: Structure, Function, and Bioinformatics, 2006, 65(1):49-54

9. Yan Wang, Zhidong Xue, Xiaohong Shi, Jin Xu. Prediction of pi-turns in proteins using PSI-BLAST profiles and secondary structure information. Biochemical and Biophysical Research Communication,2006, 347(3): 574- 580.

Courses Taught

0704581  Bioinformatics(undergraduate)

170600  Bioinformatics(graduate)


Wuhan RGSC  Cooperation. “R&D of the Big Data Platform for Medical Rehabilitation”,Dec.1st,2015-Jun.30th,2017

The Fundamental Research Funds for the Central Universities of China [2014TS138] (PI):“Prediction of protein complex interface using domain information” Jan.1st,2014-Dec.30th,2014

Huawei Tech. Cooperation Project:”R&D of the Searching Tools for Java API  I”. Dec 1st, 2013-May 31st,2014

Natural Science Fund of China 30700162 (PI):" System Biology Research of Dense Core Vesicle Secretion ", Jan. 1st, 2008 – Dec. 31st, 2010

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