报告题目：
Carbohydrate Chips for Study of Carbohydrate-Lectin Interactions Using QCM Biosensors and Microarray Technologies （QCM生物传感器和微阵列技术研究糖-蛋白、蛋白-蛋白相互作用）
时间：2010年3月22日（星期一）下午2:30
地点：生命科学与技术学院二楼会议室
报告人：裴志超博士
摘要：
Interactions between carbohydrates and proteins are increasingly being recognized as crucial in many biological processes, such as cellular adhesion and communication. In order to investigate the interactions of carbohydrates and proteins, the development of efficient analytic technologies, as well as novel strategies for the synthesis of carbohydrate chips, have to be explored. To date, several methods have been exploited to analyze interactions of carbohydrates and proteins, for example, biosensors, nuclear magnetic resonance (NMR); enzyme-linked immunosorbent assays (ELISA), X-ray crystallography and array technologies. This study describes the development of novel strategies for the synthesis of carbohydrate chips, as well as new efficient strategies to Quartz Crystal Microbalance- (QCM-) biosensors and carbohydrate microarrays technologies. These methodologies have been used to probe carbohydrate-lectin-interactions for a range of plant and animal lectins.
报告人简介：
裴志超高级研究员，现任瑞典Attana生物传感器公司高级研究员，中国科学院上海药物研究所客座教授，西北农林科技大学客座教授，郑州大学生物工程系兼职教授；瑞典华人总会常务副主席，瑞典华人博士专家协会主席。1996年曾任郑州市化工三厂厂长。2006年12月在瑞典皇家工学院化学系(化学生物学专业)获博士学位，然后留校进行短期博士后研究；主要从事糖化学生物学和生物芯片的研究。在国际著名杂志 Angew. Chem. Int. Ed.；Biosens. Bioelectron.；J. Org.Chem.；ChemBioChem.；Anal. Chem.；Anal. BioChem.；Chem Commun.；Chem. Mater.；Eur. J. Org. Chem.；Bioorg. Med. Chem. Lett.；Bioorg. Med. Chem.等发表论文二十篇。
