讲 座 信 息

单分子研究：生物分子与生物系统

Bingqian Xu

美国佐治亚大学纳米生物研究中心

生物工程系教授

时间：2009年5月18日（星期一） 上午10：00

地点：东十一楼二楼会议室

研究方向：

徐教授致力于生物分子和生物系统的单分子研究，包括纳米/单分子电子学，分子电子器件组装，生物单分子识别，生物分子（包括DNA和蛋白质）结构及性质等领域。他是扫描隧道显微镜断裂结（STM break junctions）技术的创始人 （Bingqian Xu, et al., Science, 2003），该项技术已经被广泛用于单分子电学及其他性质的研究中。此外，他还在众多国际顶级期刊，如Science, Nano letters, PNAS, J. Am. Chem. Soc., Small等上发表过重要文章。

讲座内容：

When studying systems in which molecular individuality matters, single-molecule experiments offer several important advantages over ensemble measurements.

First, single-molecule measurements provide important information that is “averaged out” in ensemble results.

    Second, by conducting many sequential measurements, they allow one to determine the distribution of molecular properties and investigate the inhomogeneous systems.

    Finally, they permit observation of rarely populated transients that are difficult or impossible to capture using bulk measurements.

The aim is to detect biological events at the single-molecule level, which will be key to scientific advances in understanding, identifying, and developing therapies that promote human health.